Pediatric Hematology, Oncology and Hematopoietic cell&gene therapy Area
Prof. Alessandra Biffi
Area Coordinator
The research area in pediatric hematology, oncology and hematopoietic cell&gene therapy belongs to the Division of Pediatric Hematology, Oncology and Stem Cell Transplant of the Padua University and Hospital and is devoted to performing cutting-edge research in:
- pediatric oncohematology, to improve diagnostics and identify novel mechanisms of tumorigenesis and new therapeutic targets;
- tumor modeling in 3D and in vivo, to enable testing of novel treatment approaches for pediatric cancer;
- hematopoietic cell and gene therapy, to develop innovative strategies for pediatric cancer, hemoglobinopathies, immune defects, neurometabolic and neurodegenerative diseases.
The mission of the group is translational in nature, with the goal of enabling therapeutic advances in pediatric hematological, oncological, metabolic diseases thanks to technology development and to a continuous dialogue between the clinical ward, the diagnostic labs and the research laboratory from bench to bedside and back.
The multidisciplinary nature of the team is at the basis of the success of the group.
LABS
Advanced Diagnostics and Target Discovery in Acute Lymphoblastic Leukemia (ALL)
Prof. Barbara Buldini | Co-Principal Investigator
Prof. Martina Pigazzi | Co-Principal Investigator
Prof. Alessandra Biffi | Co-Principal Investigator
Areas
Advanced Flow Cytometry Application in Childhood Acute Leukemia
Prof. Barbara Buldini | Principal Investigator
Transcriptomics and Functional Genomics in JMML and B ALL
Dr. Silvia Bresolin | Principal Investigator
Phosphoproteomics for ALL diagnostics and research
Dr. Valentina Serafin | Junior Principal Investigator
Advanced Diagnostics and Target Discovery in Rare Pediatric Solid Tumors
Prof. Gianni Bisogno | Principal Investigator
Biology of CNS Pediatric Tumors
Dr. Luca Persano | Principal Investigator
Experimental Pharmacology
Prof. Giampietro Viola | Principal Investigator
Subarea - High-Throughput Drug Screening for Precision Oncology
Dr. Elena Mariotto | Junior Principal Investigator
Molecular Diagnostic of Non Hodgkin Lymphoma
Prof. Lara Mussolin | Principal Investigator
Research and discovery in Hematopoietic Cell&Gene Therapy
Prof. Alessandra Biffi | Principal Investigator
Subarea - Gene therapy for hemoglobinopathies and neurometabolic diseases caused by β-Galactosidase deficiency
Dr. Valentina Poletti | Junior Principal Investigator
Target discovery and biology of acute myeloid leukemia
Prof. Martina Pigazzi | Principal Investigator
Target discovery and biology of Neuroblastoma
Dr. Sanja Aveic | Principal Investigator